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Why You Should Not Stop Taking Your Vitamins
Posted By Mark Hyman, M.D. On November 14, 2011 @ 4:35 pm In Health & Wellness, Healthy Aging | 1 Comment
How many people have died from taking vitamins?
Should you stop your vitamins?
It depends. To be exact, it depends on the quality of the science, and the very nature of scientific research. It is very hard to know things exactly through science. The waste bin of science is full of fallen heroes like Premarin, Vioxx and Avandia  (which alone was responsible for 47,000 excess cardiac deaths since it was introduced in 1999).
That brings us to the latest apparent casualty: vitamins. The recent media hype around vitamins is a classic case of drawing the wrong conclusions from good science .
Remember when doctors thought that hormone replacement therapy  was the best thing since sliced bread and recommended it to every single post-menopausal woman? These recommendations were predicated on studies that found a correlation between using hormones and reduced risk of heart attacks. But correlation does not prove cause and effect. It wasn’t until we had controlled experiments like the Women’s Health Initiative  that we learned that Premarin (hormone replacement therapy) was killing women, not saving them.
This latest study from the Archives of Internal Medicine  of 38,772 women found that “several commonly used dietary vitamin and mineral supplements may be associated with increased total mortality.” The greatest risk was from taking iron after menopause (which no doctor would ever recommend in a non-menstruating human without anemia).
The word “may” is critical here, because science is squirrelly. You only get the answers to the questions you ask. And in this case, they asked if there was an association between taking vitamins and death in older women. This type of study is called an observational study or epidemiological study. It is designed to look for or “observe” correlations. Studies like these look for clues that should then lead to further research. They are not designed to be used to guide clinical medicine or public health recommendations. All doctors and scientists know that this type of study does not prove cause and effect.
Aside from the fact that it flies in the face of an overwhelming body of research that proves that Americans are nutrient-deficient as a whole, and that nutritional supplements can have significant impact in disease prevention and health promotion, the recent study on vitamins is flawed in many other ways.
How Vitamins Save Money and Save Lives
Overwhelming basic science and experimental data support the use of nutritional supplements for the prevention of disease and the support of optimal health. The Lewin Group estimated a $24 billion savings  over 5 years if a few basic nutritional supplements were used in the elderly. Extensive literature reviews in the Journal of the American Medical Association  and the New England Journal of Medicine  also support this view. Interventional trials have proven benefit over and over again.
The concept that nutritional supplements “could be harmful” to women flies in the face of all reasonable facts from both intervention trials and outcome studies published over the past 40 years. Recent trials published within the last two years indicate that modest nutritional supplementation in middle-age women found their telomeres didn’t shorten . Keeping your teleomeres (the little end caps on your DNA) long is the hallmark of longevity and reduced risk of disease .
A plethora of experimental controlled studies — which are the gold standard for proving cause and effect — over the last few years found positive outcomes in many diseases. These include the use of calcium and vitamin D in women with bone loss; folic acid in people with cervical dysplasia (pre-cancerous lesions); iron for anemics, B-complex vitamins to improve cognitive function; zinc; vitamins C, E, and carotenoids to lower the risk of macular degeneration ; and folate and vitamin B12 to treat depression . This is but a handful of examples. There are many more.
Why Most Vitamin Studies Are Flawed
There is another important thing to understand about clinical trials that review the utility of vitamins in the treatment of disease. The studies that show harm are often designed like drug studies. For example, a study may use a high dose of vitamin E and see what happens. This is actually a prescient example also explored in recent media. Studies recently found that high doses of vitamin E and selenium didn’t prevent prostate cancer and may increase risk. What this study didn’t explore properly was the true biochemical nature of vitamin E and selenium. These nutrients work as antioxidants by donating an electron to protect or repair a damaged molecule or DNA. Once this has happened the molecules become oxidants that can cause more damage if not supported by the complex family of antioxidants used in the human body. It’s sort of like passing a hot potato. If you don’t keep passing it you will get burned. This study simply failed to take this into account.
Nature doesn’t work by giving you only one thing. We all agree that broccoli is good for you, but if that were all you ate you would die in short order. The same is true of vitamins. Nutrients are not drugs and they can’t be studied as drugs.  They are part of a biological system where all nutrients work as a team to support your biochemical processes.
Michael Jordan may have been the best basketball player in history, but he couldn’t have won six NBA titles without a team.
Obesity Is Linked to Malnutrition
The tragedy of media attention on poor studies like these is that they undermine possible solutions to some of the modern health epidemics we are facing today, and they point attention away from the real drivers of disease.
Take the case of obesity for example. Paradoxically, Americans are becoming both more obese and more nutrient deficient  at the same time. Obese children eating processed foods are nutrient depleted  and increasingly get scurvy and rickets, diseases we thought were left behind in the 19th and 20th centuries.
After treating over 15,000 patients and performing extensive nutritional testing on them, I think it is clear that Americans suffer from widespread nutrient deficiencies including vitamin D , zinc, magnesium, folate and omega-3 fats. This is supported by the government’s National Health and Nutrition Examination Survey  (NHANES) data on our population. In fact, 13 percent of our population is vitamin C deficient .
Scurvy in Americans in 2011? Really? But if all you eat is processed food — and many Americans do — then you will get scurvy, just like the British sailors of the 17th century did.
Unfortunately, negative studies on vitamins get huge media attention, while the fact that over 100,000 Americans die and 2.2 million suffer serious adverse reactions  from medication use in hospitals when used as prescribed is quietly ignored. Did you know that anti-inflammatories like aspirin and ibuprofen kill more people every year than AIDS or asthma or leukemia?
Flaws with the “Vitamins Kill You” Study
So what’s the bottom line on this study on vitamins in older white women in Iowa?
After a careful reading, a number of major flaws were identified:
In short, this recent study confuses, not clarifies, and it has only served up a dose of media frenzy and superficial analysis. It has left the consumer afraid, dazed, bewildered and reaching for the next prescription drug.
Please, don’t stop taking your vitamins. Every American needs a good quality multivitamin , vitamin D and omega-3 fat supplement. It is part of getting a metabolic tune up  and keeping your telomeres long!
To your good health,
Mark Hyman, MD
This blog post originally appeared on DrHyman.com .
Article printed from Gaiam Blog: http://blog.gaiam.com
URL to article: http://blog.gaiam.com/why-you-should-not-stop-taking-your-vitamins/
URLs in this post:
 Image: http://blog.gaiam.com/wp-content/uploads/2011/11/Multivitamins.jpg
 Avandia: http://www.ncbi.nlm.nih.gov/pubmed/20656674
 drawing the wrong conclusions from good science: http://life.gaiam.com/article/new-discoveries-are-rocking-old-rules
 hormone replacement therapy: http://life.gaiam.com/article/menopause-hormone-conundrum
 Women’s Health Initiative: http://www.nhlbi.nih.gov/whi/
 Archives of Internal Medicine: http://www.ncbi.nlm.nih.gov/pubmed/21987192
 Lewin Group estimated a $24 billion savings: http://www.huffingtonpost.com/dr-mark-hyman/how-dietary-supplements-r_b_641130.html
 Journal of the American Medical Association: http://www.ncbi.nlm.nih.gov/pubmed/12069675
 New England Journal of Medicine: http://www.ncbi.nlm.nih.gov/pubmed?term=What%20vitamins%20should%20I%20be%20taking%20doctor%3F%20willett
 their telomeres didn’t shorten: http://www.ncbi.nlm.nih.gov/pubmed/19279081
 longevity and reduced risk of disease: http://life.gaiam.com/article/3-secrets-longevity-and-vitality
 macular degeneration: http://www.ncbi.nlm.nih.gov/pubmed/21609225
 depression: http://www.ncbi.nlm.nih.gov/pubmed/19769453
 Nutrients are not drugs and they can’t be studied as drugs.: http://drhyman.com/paradigm-shift-the-end-of-normal-science-in-medicine-3135/
 obese and more nutrient deficient: http://www.ncbi.nlm.nih.gov/pubmed/21854698
 Obese children eating processed foods are nutrient depleted: http://www.ncbi.nlm.nih.gov/pubmed/21704500
 vitamin D: http://www.ncbi.nlm.nih.gov/pubmed/18191047
 National Health and Nutrition Examination Survey: http://www.cdc.gov/nutritionreport/
 vitamin C deficient: http://www.ajcn.org/content/90/5/1252.abstract
 100,000 Americans die and 2.2 million suffer serious adverse reactions: http://jama.ama-assn.org/content/279/15/1200.full
 synthetic folic acid can cause cancer, while natural folate is protective: http://www.huffingtonpost.com/dr-mark-hyman/nutrition-tips-folic-acid_b_601126.html
 CDC: http://www.cdc.gov/nchs/data/nvsr/nvsr59/nvsr59_04.pdf
 good quality multivitamin: http://life.gaiam.com/article/whats-multivitamin
 metabolic tune up: http://www.ncbi.nlm.nih.gov/pubmed/14989256
 getting a metabolic tune up: http://drhyman.com/how-to-give-yourself-a-metabolic-tune-up-2-5473/
 DrHyman.com: http://www.drhyman.com/
 DrHyman.com: http://drhyman.com/why-you-should-not-stop-taking-your-vitamins-7781/
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