The worst mistake I have made was to compromise on these core principles. For example, toward the end of our first period of very rapid growth (45 percent a year for five years), we hired several wonderful, spirited managers. However, they were not entrepreneurs; and they never could, partly in consequence, intuitively "get" our vision, our core stakeholders, or our culture. They set to work managing, which ended in failure, uncomprehending frustration, and culture division. Good entrepreneurs can manage, but no one but an entrepreneur can entrepreneur, let alone help build and lead the world's community of leading social entrepreneurs and their top business entrepreneur allies.
Source: America's Best Leaders: Q&A with Bill Drayton, founder of Ashoka: http://www.usnews.com/usnews/news/articles/051022/22drayton.htm
Contributed by: ~C4Chaos